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Information on the latest vitamin D news and research.

Find out more information on deficiency, supplementation, sun exposure, and how vitamin D relates to your health.

Vitamin D study on cardiometabolic risks set to get underway

Researchers will be investigating the effect of vitamin D supplements on cardiometabolic risks and quality of life of premenopausal women in Malaysia. Cardiometabolic risk factors are risks that increase a person’s overall risk for type II diabetes and cardiovascular disease. The risk factors include being overweight or obese, high blood sugar, high blood pressure, lack of physical activity, smoking habit, inflammation, and abnormal cholesterol levels.

Mazilza Ramly, MD and colleagues will be conducting a double blind, randomized controlled trial including 320 premenopausal women working at a university in Malaysia. The women will be randomized to receive either 50,000 IU vitamin D weekly for 8 weeks followed by 50,000 IU monthly for 10 months, or a placebo for 12 months. All participants will be vitamin D deficient (<20 ng/ml) at baseline.

Vitamin D status of all participants will be collected multiple times throughout the study. Blood pressure, cholesterol levels, blood glucose and insulin, serum parathyroid hormone, and calcium levels will be assessed at baseline, 6 months and 12 months. Quality of life will be measured at baseline and one year.

This research will contribute to the emerging body of evidence of vitamin D in the prevention for cardiometabolic disease. The authors are currently recruiting participants. To find out more information about the study contact Mazliza Ramly at drmazliza@wp.moh.gov.my. We’ll be reporting the results once the study is complete and results published.


Ramly M, et al. Study protocol: the effect of vitamin D supplements on cardiometabolic risk factors among urban premenopausal women in a tropical country – a randomized controlled trial. BMC Public Health, 2013.