VDC test kit slider
VDC-Banner-new_468
VDC test kit slider
sunfriend-banner
sperti logo 1
Text size A A A
High contrast on off

Information on the latest vitamin D news and research.

Find out more information on deficiency, supplementation, sun exposure, and how vitamin D relates to your health.

Vitamin D-binding protein levels likely unimportant in vitamin D status

Last December I wrote about a study in the New England Journal of Medicine by Powe et al. that suggested the amount of bioavailable vitamin D was about the same in blacks and whites living in the United States, although it is well known that total levels of vitamin D are much lower in U.S. blacks. The study suggested, based on the bone-mineral density paradox (blacks typically have higher BMD than whites), that vitamin D status has nothing to do with the health differences between U.S. blacks and whites, although vitamin D status has been associated with racial health disparities in at least 27 other studies.

Bioavailable vitamin D is defined as 25(OH)D that is not bound to vitamin D-binding protein (DBP), a blood protein similar to the major blood protein, albumin, but much less abundant.

You need to be logged in to read the rest of this post. Please log in or become a member.

  About: Tom Weishaar

After a career writing about computers and personal finance, Tom Weishaar is a doctoral student in the health education program at Teachers College, Columbia University.

One Response to Vitamin D-binding protein levels likely unimportant in vitamin D status

  1. Here are 15 studies on Vitamin D binding Protein
    http://www.vitamindwiki.com/tiki-browse_categories.php?parentId=143&deep=off&type=
    Here are the titles
    Vitamin D can be somewhat blocked by Vitamin D Binding Protein – May 2014
    Vitamin D binding protein: a multifunctional protein of clinical importance – book chapter May 2014
    Bone density correlates better with free D (calculated) rather than measured vitamin D – Jan 2014
    5X less risk of Kidney cancer if good ratio of Vitamin D binding protein to circulating vitamin D – Nov 2013
    One test to estimate Vitamin D, A, Cu, Se, etc : measure proteins in blood – Oct 2013
    Hypothesis: Vitamin D Binding Protein limits vitamin D benefits outside of kidney too– Oct 2013
    Response to vitamin D related to DBP and CYP2RI genes – Aug 2013
    4,000 IU vitamin D did not change 25OHD to Vitamin D Binding Protein ratio for obese – RCT April 2013
    Common Vitamin D gene variants and resulting diseases – Jan 2013
    Vitamin D level can be high, but little benefit: due to kidney, genes, low Magnesium etc.
    Late-stage MS associated with protein in spinal cord which blocks vitamin D – Jan 2013
    Vitamin D Binding Protein, And Airflow In COPD – April 2012
    Pancreatic Cancer with high levels of Vitamin D and Vitamin D Binding Protein – Mar 2012
    Type 1 diabetes patients may be pissing away vitamin D – Jan 2011
    How vitamin D helps the lung via vitamin D-binding protein – May 2010