Preventing inflammation is all the rage. Dark chocolate, tea, pomegranate juice, berries, and vegetables are a few of the mainstays of an anti-inflammatory diet.
What about vitamin D and inflammation? Recently, Dr Uwe Querfeld of the Charité Children’s Hospital in Germany reviewed the world’s literature on vitamin D and inflammation.
Dr. Querfeld found:
- “It has recently become evident that renal and cardiovascular disease often develops in parallel and influences each other. This has been described as cardio-renal syndrome.”
- CRP levels or C-reactive protein (a marker of inflammation) are an independent predictor of all-cause and cardiovascular mortality.
- “Subjects with low vitamin D levels and high CRP serum concentrations had the shortest leukocyte telomere length, indicating a higher cumulative burden of oxidative stress and inflammation.”
- Vitamin D inhibits the activation the TNF alpha converting enzyme, which has an important role in the generation of inflammation.
- Vitamin D also appears to control inflammation through regulation of the transcription factor NF-κB.
- “There is likely a whole spectrum of interrelated beneficial effects and potential mechanisms by which vitamin D may lower cardiovascular risk.”
- “Randomized controlled studies examining the effect of vitamin D administration on inflammatory markers and cardiovascular outcomes are clearly needed.”
Wait for randomized controlled trials if you want. As for me, I will continue to maintain natural vitamin D blood levels (50-60 ng/ml), while I wait for scientists to do their work.